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Article

Are there non-catalytic functions of acetylcholinesterases? Lessons from mutant animal models.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2005

Cousin Xavier, Strähle Uwe, Chatonnet Arnaud

Abstract excerpt

Acetylcholinesterase (AChE) hydrolyses acetylcholine (ACh) ensuring the fast clearance of released neurotransmitter at cholinergic synapses. Many studies led to the hypothesis that AChE and the closely related enzyme butyrylcholinesterase (BChE) may play other, non-hydrolytic roles during development. In this review, we compare data from in vivo studies performed on invertebrate and vertebrate genetic models. The...

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Identifiers

PMID: 15666354
DOI: 10.1002/bies.20153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Are there non-catalytic functions of acetylcholinesterases? Lessons from mutant animal models.PMID 15666354Read ↗

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Zebrafish mutants of the neuromuscular junction: swimming in the gene pool.Semantic proximity Read ↗

Knockout of one acetylcholinesterase allele in the mouse.Semantic proximity Read ↗

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