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Article

Changes of proliferative activity and phenotypes in spontaneous differentiation of a colon cancer cell line.

Japanese journal of cancer research : Gann - 1 Jun 1993

Hara A, Hibi T, Yoshioka M, Toda K, Watanabe N, Hayashi A, Iwao Y, Saito H, Watanabe T, Tsuchiya M

Abstract excerpt

We examined the alterations of proliferative activity and c-myc expression of a colon cancer cell line (Caco-2) during its spontaneous differentiation. Caco-2 cells were cultured in various types of media and the degree of differentiation was monitored in terms of dome formation in cell monolayers and expression of alkaline phosphatase (ALP) activity. In Caco-2 cells cultured with Eagle's minimum essential medium...

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Identifiers

PMID: 8393433
DOI: 10.1111/j.1349-7006.1993.tb02022.x
PMCID: PMC5919322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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