Article
Multilineage differentiation of cloned HRA-19 cells in serum-free medium: a model of human colorectal epithelial differentiation.
Differentiation; research in biological diversity - 1 Jul 1996
Henderson K, Kirkland S C
Abstract excerpt
Colorectal epithelium is composed of polarised absorptive enterocytes, mucus-producing goblet cells and enteroendocrine cells. All these cell lineages are thought to arise from multipotential stem cells located near the base of the crypt, but the mechanisms which control differentiation and commi...
Topics
- Cell Differentiation
- Cell Lineage
- Clone Cells
- Colorectal Neoplasms
- Culture Media, Serum-Free
- Humans
- Intestinal Absorption
- Intestinal Mucosa
- Microscopy, Electron
- Microscopy, Electron, Scanning
- Microvilli
- Models, Biological
- Phenotype