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Article

Prognostic significance of Bcl-2 in invasive mammary carcinomas: a comparative clinicopathologic study between "triple-negative" and non-"triple-negative" tumors.

Human pathology - 1 Jan 2012

Tawfik Kareem, Kimler Bruce F, Davis Marilyn K, Fan Fang, Tawfik Ossama

Abstract excerpt

Bcl-2 is a tumorigenic protein that is expressed in 25% to 50% of breast cancers. Although its expression has been widely accepted as a favorable prognostic marker, its protective mechanism of action remains unclear. "Triple-negative" tumors are an aggressive subgroup known to carry a poor prognosis. Studies documenting prognostic significance of Bcl-2 expression in triple-negative in comparison to...

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Share to Carcinoma, Ductal, Breast
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphatic Metastasis

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Share to Neoplasms, Multiple Primary

Share to Proto-Oncogene Proteins c-bcl-2

Share to Receptors, Progesterone

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Identifiers

PMID: 21777944
DOI: 10.1016/j.humpath.2011.04.011

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