Article
Clinical significance of p53 and bcl-2 protein coexpression phenotypes in molecular breast cancer subtypes of pre-menopausal and post-menopausal African-American women.
The American surgeon - 1 Sept 2009
Ihemelandu Chukwuemeka U, Dewitty Robert L, Leffall Lasalle D, Suryanarayana Siram M, Frederick Wayne A
Abstract excerpt
With the current classification of breast carcinoma into molecular subtypes with distinct prognosis and response to therapy, we sort to assess the clinical significance of p53 and bcl-2 coexpression phenotypes in invasive breast tumors and correlate this to the different molecular breast cancer subtypes in African-American women. We performed a retrospective analysis of data on p53 and bcl-2 expression. Results...
Topics
- Adult
- Black or African American
- Aged
- Aged, 80 and over
- Breast Neoplasms
- DNA, Neoplasm
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Immunohistochemistry