Regulators of apoptosis in human breast cancer.

doi:10.1016/s0009-9120(99)00025-9

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Regulators of apoptosis in human breast cancer.

Clinical biochemistry - 1 Jul 1999

Eissa S, Labib R, Khalifa A, Swelam N, Khalil F, El-Shenawy A M

Abstract excerpt

OBJECTIVES: Apoptosis or programmed cell death represents a mechanism by which tumor cells with DNA damage can be deleted. Bcl-2 and p53 gene products have been both linked to apoptosis. Bcl-2 plays a role as an inhibitor of apoptosis that may extend the viability of cells containing genetic alterations and facilitate tumor progression. Mutant p53 has a similar effect. The purpose of this study was to investigate...

Topics

Adult
Aged
Aneuploidy
Apoptosis
Blotting, Western
Breast
Breast Neoplasms
Female
Gene Expression
Gene Expression Regulation, Neoplastic
Genes, bcl-2
Humans
Immunoblotting
Middle Aged
Mutation
Proto-Oncogene Proteins c-bcl-2
Receptors, Estrogen
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 10480445
DOI: 10.1016/s0009-9120(99)00025-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics