Article
Relating three-dimensional structures to protein networks provides evolutionary insights.
Science (New York, N.Y.) - 22 Dec 2006
Kim Philip M, Lu Long J, Xia Yu, Gerstein Mark B
Abstract excerpt
Most studies of protein networks operate on a high level of abstraction, neglecting structural and chemical aspects of each interaction. Here, we characterize interactions by using atomic-resolution information from three-dimensional protein structures. We find that some previously recognized rel...
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