Article
Modularity and intrinsic evolvability of Hsp90-buffered change.
PloS one - 20 Dec 2006
Carey Charles C, Gorman Kristen F, Rutherford Suzannah
Abstract excerpt
Hsp90 controls dramatic phenotypic transitions in a wide array of morphological features of many organisms. The genetic-background dependence of specific abnormalities and their response to laboratory selection suggested Hsp90 could be an 'evolutionary capacitor', allowing developmental variation to accumulate as neutral alleles under normal conditions and manifest selectable morphological differences during...
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