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Article

Quantitative trait symmetry independent of Hsp90 buffering: distinct modes of genetic canalization and developmental stability.

Proceedings of the National Academy of Sciences of the United States of America - 11 Nov 2003

Milton Claire C, Huynh Brandon, Batterham Philip, Rutherford Suzanne L, Hoffmann Ary A

Abstract excerpt

The Hsp90 chaperone buffers development against a wide range of morphological changes in many organisms and in Drosophila masks the effects of hidden genetic variation. Theory predicts that genetic and nongenetic buffering will share common mechanisms. For example, it is argued that Hsp90 genetic buffering evolved solely as a by-product of environmental buffering, and that Hsp90 should mask morphological...

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Identifiers

PMID: 14595030
DOI: 10.1073/pnas.1835613100
PMCID: PMC263825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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