Article

Threshold trait architecture of Hsp90-buffered variation

2015-03-25

Abstract excerpt

Common genetic variants buffered by Hsp90 are candidates for human diseases of signaling such as cancer. Like cancer, morphological abnormalities buffered by Hsp90 are discrete threshold traits with a continuous underlying basis of liability determining their probability of occurrence. QTL and deletion maps for one of the most frequent Hsp90-dependent abnormalities in Drosophila, deformed eye ( dfe ), were replic...

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Literature Corpus work: aa5940e1-621b-570c-845a-2e67cc1a18c3
DOI: 10.1101/016980

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