Article
Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution.
Nature genetics - 1 Jan 2003
Sollars Vincent, Lu Xiangyi, Xiao Li, Wang Xiaoyan, Garfinkel Mark D, Ruden Douglas M
Abstract excerpt
Morphological alterations have been shown to occur in Drosophila melanogaster when function of Hsp90 (heat shock 90-kDa protein 1alpha, encoded by Hsp83) is compromised during development. Genetic selection maintains the altered phenotypes in subsequent generations. Recent experiments have shown, however, that phenotypic variation still occurs in nearly isogenic recombinant inbred strains of Arabidopsis thaliana....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.