Article
Hsp90 and developmental networks.
Advances in experimental medicine and biology - 1 Jan 2007
Rutherford Suzannah, Knapp Jennifer R, Csermely Peter
Abstract excerpt
The most abundant cytoplasmic chaperone of eukaryotic cells, Hsp90 is a hub in developmental regulatory networks and the first example described of the phenomenon of molecular buffering. As a chaperone for many different signaling proteins, Hsp90 maintains the clarity and strength of communication within and between cells, concealing developmental and stochastic variations that otherwise cause abrupt...
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