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Article

Hsp90 as a capacitor for morphological evolution.

Nature - 26 Nov 1998

Rutherford S L, Lindquist S

Abstract excerpt

The heat-shock protein Hsp90 supports diverse but specific signal transducers and lies at the interface of several developmental pathways. We report here that when Drosophila Hsp90 is mutant or pharmacologically impaired, phenotypic variation affecting nearly any adult structure is produced, with specific variants depending on the genetic background and occurring both in laboratory strains and in wild...

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PMID: 9845070
DOI: 10.1038/24550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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