Article
Maximum-likelihood estimation of allelic dropout and false allele error rates from microsatellite genotypes in the absence of reference data.
Genetics - 1 Feb 2007
Johnson Paul C D, Haydon Daniel T
Abstract excerpt
The importance of quantifying and accounting for stochastic genotyping errors when analyzing microsatellite data is increasingly being recognized. This awareness is motivating the development of data analysis methods that not only take errors into consideration but also recognize the difference between two distinct classes of error, allelic dropout and false alleles. Currently methods to estimate rates of allelic...
Topics
- Alleles
- Animals
- Computer Simulation
- Foxes
- Genotype
- Heterozygote
- Inbreeding
- Likelihood Functions
- Microsatellite Repeats
- Sample Size
- Software
- Wolves