Article
Genotyping Error Detection and Customised Filtration for SNP Datasets.
Molecular ecology resources - 1 Jan 2025
Kan-Lingwood Noa Yaffa, Sagi Liran, Mazie Shahar, Shahar Naama, Zecherle Bitton Lilith, Templeton Alan, Rubenstein Daniel, Bouskila Amos, Bar-David Shirli
Abstract excerpt
A major challenge in analysing single-nucleotide polymorphism (SNP) genotype datasets is detecting and filtering errors that bias analyses and misinterpret ecological and evolutionary processes. Here, we present a comprehensive method to estimate and minimise genotyping error rates (deviations from the 'true' genotype) in any SNP datasets using triplicates (three repeats of the same sample) in a four-step...
Topics
- Polymorphism, Single Nucleotide
- Genotyping Techniques
- Animals
- Genotype
- Computational Biology