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Article

High-fidelity, large-scale targeted profiling of microsatellites.

Genome research - 20 Aug 2024

Loh Caitlin A, Shields Danielle A, Schwing Adam, Evrony Gilad D

Abstract excerpt

Microsatellites are highly mutable sequences that can serve as markers for relationships among individuals or cells within a population. The accuracy and resolution of reconstructing these relationships depends on the fidelity of microsatellite profiling and the number of microsatellites profiled. However, current methods for targeted profiling of microsatellites incur significant "stutter" artifacts that...

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Topics

Microsatellite Repeats
Humans
Genotyping Techniques
Genotype
Sequence Analysis, DNA

Source

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Identifiers

PMID: 39013593
DOI: 10.1101/gr.278785.123
PMCID: PMC11368184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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