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Enhanced low-template DNA analysis conditions and investigation of allele dropout patterns.

Forensic science international. Genetics - 1 Jan 2015

Hedell Ronny, Dufva Charlotte, Ansell Ricky, Mostad Petter, Hedman Johannes

Abstract excerpt

Forensic DNA analysis applying PCR enables profiling of minute biological samples. Enhanced analysis conditions can be applied to further push the limit of detection, coming with the risk of visualising artefacts and allele imbalances. We have evaluated the consecutive increase of PCR cycles from 30 to 35 to investigate the limitations of low-template (LT) DNA analysis, applying the short tandem repeat (STR)...

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PMID: 25282604
DOI: 10.1016/j.fsigen.2014.09.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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