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Article

Likelihood-based estimation of microsatellite mutation rates.

Genetics - 1 Jun 2003

Whittaker John C, Harbord Roger M, Boxall Nicola, Mackay Ian, Dawson Gary, Sibly Richard M

Abstract excerpt

Microsatellites are widely used in genetic analyses, many of which require reliable estimates of microsatellite mutation rates, yet the factors determining mutation rates are uncertain. The most straightforward and conclusive method by which to study mutation is direct observation of allele transmissions in parent-child pairs, and studies of this type suggest a positive, possibly exponential, relationship between...

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Identifiers

PMID: 12807796
DOI: 10.1093/genetics/164.2.781
PMCID: PMC1462577

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