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Article

Amino-acid residues involved in glutamate receptor 6 kainate receptor gating and desensitization.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Feb 2003

Fleck Mark W, Cornell Elizabeth, Mah Stephanie J

Abstract excerpt

The glutamate receptor (GluR) agonist-binding site consists of amino acid residues in the extracellular S1 and S2 segments in the N-terminal and M3-M4 loop regions, respectively. Molecular and atomic level structural analyses have identified specific S1 and S2 residues that interact directly with ligands, interact with one another in a dimeric configuration, and influence channel gating and desensitization...

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Source

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Identifiers

PMID: 12598610
PMCID: PMC6742261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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