Article
Divergent evolution of the prolactin-inducible protein gene and related genes in the mouse genome.
Gene - 21 Jan 2004
Osawa Motoki, Horiuchi Hidekazu, Tian Wei, Kaneko Mika
Abstract excerpt
The prolactin-inducible protein (PIP/GCDFP15) family consists of small secretory polypeptides that are found in various body fluids. In order to study evolutionary events to this family, we cloned member genes and analyzed their sequences. A database search revealed the presence of a novel paralogous gene on mouse chromosome 6q34 and a nonprocessed pseudogene adjacent to PIP on human chromosome 7q34. The mouse...
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