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The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta.

Developmental biology - 1 May 2010

Jerome-Majewska Loydie A, Achkar Tala, Luo Li, Lupu Floria, Lacy Elizabeth

Abstract excerpt

During vesicular transport between the endoplasmic reticulum and the Golgi, members of the TMED/p24 protein family form hetero-oligomeric complexes that facilitate protein-cargo recognition as well as vesicle budding. In addition, they regulate each other's level of expression. Despite analyses of TMED/p24 protein distribution in mammalian cells, yeast, and C. elegans, little is known about the role of this...

Topics

Animals
Embryo, Mammalian
Endoplasmic Reticulum
Female
Gene Expression Regulation, Developmental
Membrane Proteins
Mice
Mice, Inbred C57BL
Morphogenesis
Mutation
Placenta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy

Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20178780
DOI: 10.1016/j.ydbio.2010.02.019
PMCID: PMC2892723

Genes

TMED2
TMED10
TMED7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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