Article
Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition.
Development (Cambridge, England) - 1 Dec 2014
Naruse Mie, Ono Ryuichi, Irie Masahito, Nakamura Kenji, Furuse Tamio, Hino Toshiaki, Oda Kanako, Kashimura Misho, Yamada Ikuko, Wakana Shigeharu, Yokoyama Minesuke, Ishino Fumitoshi, Kaneko-Ishino Tomoko
Abstract excerpt
Sirh7/Ldoc1 [sushi-ichi retrotransposon homolog 7/leucine zipper, downregulated in cancer 1, also called mammalian retrotransposon-derived 7 (Mart7)] is one of the newly acquired genes from LTR retrotransposons in eutherian mammals. Interestingly, Sirh7/Ldoc1 knockout (KO) mice exhibited abnormal placental cell differentiation/maturation, leading to an overproduction of placental progesterone (P4) and placental...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.