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Article

Down-regulation of Sox10 with specific small interfering RNA promotes transdifferentiation of Schwannoma cells into myofibroblasts.

Differentiation; research in biological diversity - 1 Dec 2006

Roh Jiwon, Cho Eun-ah, Seong Ikjoo, Limb Jin-kyung, Lee Sanghyuk, Han Sung-jun, Kim Jaesang

Abstract excerpt

Neural crest-derived cells are noted for the long lasting plasticity during lineage commitment process and the potential for transdifferentiation into other neural crest derivatives. Schwann cells in particular have been reported to transdifferentiate into melanocytes and myofibroblasts. Detailed studies of transdifferentiation at the molecular level have been hampered by difficulty in isolating sufficient...

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PMID: 17177851
DOI: 10.1111/j.1432-0436.2006.00084.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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