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Article

WIF1, an inhibitor of the Wnt pathway, is rearranged in salivary gland tumors.

Genes, chromosomes & cancer - 1 Mar 2007

Queimado Lurdes, Lopes Carla S, Reis Antonio M C

Abstract excerpt

Chromosome rearrangements involving 12q13-15 are frequent among several tumors, including pleomorphic adenomas. The common molecular target for these aberrations is the HMGA2 gene, but various fusion partners of HMGA2 have been reported in tumors. Here we report the identification of the WNT inhibitory factor 1 (WIF1) gene as a novel HMGA2 fusion partner in a salivary gland pleomorphic adenoma. In normal salivary...

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Topics

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Share to Carcinoma, Adenoid Cystic
Share to Chromosome Aberrations
Share to Chromosomes, Human, Pair 12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HMGA2 Protein

Share to Oncogene Proteins, Fusion

Share to Salivary Gland Neoplasms

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Source

Identifiers

PMID: 17171686
DOI: 10.1002/gcc.20402

Genes

WIF1
HMGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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