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Article

Consistent PLAG1 and HMGA2 abnormalities distinguish carcinoma ex-pleomorphic adenoma from its de novo counterparts.

Human pathology - 1 Jan 2015

Katabi Nora, Ghossein Ronald, Ho Alan, Dogan Snjezana, Zhang Lei, Sung Yun-Shao, Antonescu Cristina R

Abstract excerpt

Carcinoma ex-pleomorphic adenoma (CA ex-PA) is a malignant salivary gland tumor that arises in association with pleomorphic adenoma (PA). Both PA and CA ex-PA have a broad spectrum of histology, and distinction from their histologic mimics may be difficult based on morphology alone. PLAG1 and HMGA2 abnormalities are the most common genetic events in both PA and CA ex-PA; however, the use of PLAG1 and HMGA2 as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25439740
DOI: 10.1016/j.humpath.2014.08.017
PMCID: PMC4768723

Genes

HMGA2
PLAG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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