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Article

HMGA2-positive salivary gland neoplasms with prominent trabecular/canalicular morphology: a focus on carcinomas arising within this phenotype.

Histopathology - 1 Feb 2025

Dababneh Melad N, Azzato Elizabeth M, Nakitandwe Joy, Cracolici Vincent, Shah Akeesha A

Abstract excerpt

AIMS: Pleomorphic adenoma (PA) with a prominent trabecular/canalicular morphology has consistent HMGA2 protein expression, and association with HMGA2 fusions. We report our experience with this subtype, with emphasis on the carcinomas that can arise in this context. METHODS AND RESULTS: A retro- and prospective review (2013-2024) of major salivary gland tumours with prominent trabecular/canalicular morphology was...

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PMID: 39360582
DOI: 10.1111/his.15334

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