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Article

Targets of genome copy number reduction in primary breast cancers identified by integrative genomics.

Genes, chromosomes & cancer - 1 Mar 2007

Chen Wei, Salto-Tellez Manuel, Palanisamy Nallasivam, Ganesan Kumaresan, Hou Qingsong, Tan Lay Keng, Sii Lang Hiong, Ito Kosei, Tan Benita, Wu Jeanie, Tay Andrew, Tan Kok Chai, Ang Erik, Tan Bien Keem, Tan Puay Hoon, Ito Yoshiaki, Tan Patrick

Abstract excerpt

The identification of specific oncogenes and tumor suppressor genes in regions of recurrent aneuploidy is a major challenge of molecular cancer research. Using both oligonucleotide single-nucleotide polymorphism and mRNA expression arrays, we integrated genomic and transcriptional information to identify and prioritize candidate cancer genes in regions of increased and decreased chromosomal copy number in a...

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Identifiers

PMID: 17171680
DOI: 10.1002/gcc.20411

Genes

RUNX3
ARPIN
FBN1
LZTS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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