Article
Molecular cloning and characterization of alpha1-soluble guanylyl cyclase gene promoter in rat pituitary cells.
Journal of molecular endocrinology - 1 Dec 2006
Jiang Yonghua, Stojilkovic Stanko S
Abstract excerpt
Soluble guanylyl cyclase is a cytosolic enzyme which catalyzes conversion of GTP to the second messenger cyclic GMP. The transcriptional regulation at the promoter levels of four soluble guanylyl cyclase subunits, termed alpha1, alpha2, beta1, and beta2, is largely unknown. In this study, we identified the transcription start site of alpha1-soluble guanylyl cyclase gene in rat pituitary cells and cloned the 3.5...
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