Article
Characterization of a steroidogenic factor-1-binding site found in promoter of sterol carrier protein-2 gene.
Endocrine - 1 Mar 2001
Lopez D, Shea-Eaton W, McLean M P
Abstract excerpt
Sterol carrier protein-2 (SCP2) is thought to mediate intracellular cholesterol transport in steroidogenic tissues. To elucidate the mechanism underlying the expression of this gene, a 300-bp fragment of the SCP2 promoter was cloned and analyzed for regulatory motifs. This promoter region contained a SF-1 binding motif, three activator protein-1 elements, an insulin response element, and a peroxisomal...
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