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Article

Characterization of the role of Sp1 and NF-Y in differential regulation of PTTG/securin expression in tumor cells.

Gene - 11 Dec 2003

Clem Amy L, Hamid Tariq, Kakar Sham S

Abstract excerpt

Pituitary tumor transforming gene (PTTG), also known as securin, is a regulator of cell division that is overexpressed in many tumors. Its expression is cell cycle regulated, although its transcriptional regulation is yet to be determined. The 5' RACE analysis of the human testis mRNA revealed the existence of a previously unreported transcription start site at 317 bp upstream of the translation start site (ATG)....

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Identifiers

PMID: 14644503
DOI: 10.1016/j.gene.2003.08.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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