Article
Regulation of guanylyl cyclase/natriuretic peptide receptor-A gene expression.
Peptides - 1 Jun 2005
Garg Renu, Pandey Kailash N
Abstract excerpt
Natriuretic peptide receptor-A (NPRA) is the biological receptor of the peptide hormones atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). The level and activity of this receptor determines the biological effects of ANP and BNP in different tissues mainly directed towards the maintenance of salt and water homeostasis. The core transcriptional machinery of the TATA-less Npr1 gene, which encodes...
Topics
- Animals
- Base Sequence
- Binding Sites
- Female
- Gene Expression Regulation
- Genome, Human
- Guanylate Cyclase
- Homeostasis
- Humans
- Hypertension
- Introns
- Mice
