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Article

Calnexin regulated gonadotropin-releasing hormone receptor plasma membrane expression.

Journal of molecular endocrinology - 1 Dec 2006

Brothers Shaun P, Janovick Jo Ann, Conn P Michael

Abstract excerpt

A significant proportion of human gonadotropin-releasing hormone receptors (GnRHRs) are normally retained in the endoplasmic reticulum (ER); however, nearly all rat GnRHRs are routed to the plasma membrane. When mutations are introduced into either receptor, considerably more of the proteins are recognized by the quality control system (QCS) as misfolded and retained compared with wild-type (WT) receptor,...

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Identifiers

PMID: 17170088
DOI: 10.1677/jme.1.02142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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