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Article

Ortho-quinones of benzene and estrogens induce hyperproliferation of human peripheral blood mononuclear cells.

Leukemia & lymphoma - 1 Dec 2006

Chakravarti Dhrubajyoti, Zahid Muhammad, Backora Matthew, Myers Erin M, Gaikwad Nilesh, Weisenburger Dennis D, Cavalieri Ercole L, Rogan Eleanor G, Joshi Shantaram S

Abstract excerpt

Benzene is a known leukemogen. It has been hypothesized that benzene and natural estrogens initiate cancer by forming ortho-quinones (catechol quinones) that react with DNA in cells. These quinones form depurinating DNA adducts that generate the mutations leading to cancer. This study examined wh...

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Source

Identifiers

PMID: 17169809
DOI: 10.1080/10428190600931937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17169809-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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