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Article

Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity.

Chemico-biological interactions - 30 May 2005

Iskander Karim, Jaiswal Anil K

Abstract excerpt

Quinone oxidoreductases (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic reduction of quinones and its derivatives to protect cells against redox cycling and oxidative stress. In humans, a high percentage of individuals with myeloid and other types of leukemia are homo- and heterozygous for a null mutant allele of NQO1. The NQO2 locus is also highly polymorphic in humans. Recently, we generated...

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Source

Identifiers

PMID: 15935811
DOI: 10.1016/j.cbi.2005.03.019

Genes

NQO1
NQO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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