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Article

Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers.

Journal of toxicology and environmental health. Part B, Critical reviews - 1 Jan 2000

Roy Deodutta, Cai Qiuyin, Felty Quentin, Narayan Satya

Abstract excerpt

In addition to the direct effect of estrogen on mitochondria and the redox cycling of catechol estrogen, estrogen-induced proinflammatory cytokines, such as interleukin-1 beta (IL-1beta) and tumor necrosis factor alpha (TNF-alpha), also generate reactive oxygen and nitrogen species (RO/NS). Diffe...

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Source

Identifiers

PMID: 17620201
DOI: 10.1080/15287390600974924

Genes

TNF
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17620201-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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