Article
Alzheimer's disease: genetic studies and transgenic models.
Annual review of genetics - 1 Jan 1998
Price D L, Tanzi R E, Borchelt D R, Sisodia S S
Abstract excerpt
Recent advances in a variety of areas of research, particularly in genetics and in transgenic (Tg)/gene targeting approaches, have had a substantial impact on our understanding of Alzheimer's disease (AD) and related disorders. After briefly reviewing the progress that has been made in diagnostic...
Topics
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Animals
- Apolipoproteins E
- Caenorhabditis elegans
- Disease Models, Animal
- Humans
- Membrane Proteins
- Mice
- Mice, Knockout
- Mice, Transgenic
- Mutation
- Phenotype
- Presenilin-1
- Presenilin-2