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Article

Alzheimer's disease: genetic studies and transgenic models.

Annual review of genetics - 1 Jan 1998

Price D L, Tanzi R E, Borchelt D R, Sisodia S S

Abstract excerpt

Recent advances in a variety of areas of research, particularly in genetics and in transgenic (Tg)/gene targeting approaches, have had a substantial impact on our understanding of Alzheimer's disease (AD) and related disorders. After briefly reviewing the progress that has been made in diagnostic assessments of patients with senile dementia and in investigations of the neuropathology of AD, we discuss some of the...

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PMID: 9928488
DOI: 10.1146/annurev.genet.32.1.461

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