Article
Derivation of mixed phenotype cell lines with ras-myc- and raf-myc-containing retroviral vectors after infection of murine long-term bone marrow cultures.
Experimental hematology - 1 Aug 1991
Spoor E, Ziegler S F, Overell R W, deVries P, Williams D E
Abstract excerpt
Murine long-term bone marrow cultures were infected with retroviral vectors expressing the viral ras, raf, and myc oncogenes, alone and in combination. Stably transformed clonal cell lines were obtained after infection with ras-myc and raf-myc retroviruses but not by vectors expressing ras, myc,...
Topics
- Acetylcholinesterase
- Animals
- Bone Marrow
- Bone Marrow Cells
- DNA
- Genes, myc
- Genes, ras
- Histocytochemistry
- Mice
- Mice, Inbred C57BL
- Naphthol AS D Esterase
- Phenotype
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-raf
- RNA
- Retroviridae
- Staining and Labeling
- Transfection