Article
Mixed phenotype murine leukemias.
Leukemia - 1 Aug 1993
Defresne M P, Borremans B, Verhofstede C, Peled A, Thiry A, Greimers R, Robberecht P, Nabarra B, Verschaeve L, Hooghe R
Abstract excerpt
Cell lines were derived from eight individual leukemias induced by X-rays in NFS mice. First typed as null cells (surface immunoglobulin negative, Thy-1 negative), they turned out to have a mixed phenotype with myeloid cytochemical markers, pre-B surface antigens and molecular markers of pro-B lymphocytes. They represent murine models for mixed phenotype (pro-pre-B-myeloid) leukemias.
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