Article
Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2006
Agudo Antonio, Sala Núria, Pera Guillem, Capellá Gabriel, Berenguer Antonio, García Nadia, Palli Domenico, Boeing Heiner, Del Giudice Giuseppe, Saieva Calogero, Carneiro Fatima, Berrino Franco, Sacerdote Carlotta, Tumino Rosario, Panico Salvatore, Berglund Göran, Simán Henrik, Stenling Roger, Hallmans Göran, Martínez Carmen, Bilbao Roberto, Barricarte Aurelio, Navarro Carmen, Quirós José R, Allen Naomi, Key Tim, Bingham Sheila, Khaw Kay-Tee, Linseisen Jakob, Nagel Gabriele, Overvad Kim, Tjonneland Anne, Olsen Anja, Bueno-de-Mesquita H Bas, Boshuizen Hendriek C, Peeters Petra H, Numans Mattijs E, Clavel-Chapelon Françoise, Boutron-Ruault Marie-Christine, Trichopoulou Antonia, Lund Eiliv, Offerhaus Johan, Jenab Mazda, Ferrari Pietro, Norat Teresa, Riboli Elio, González Carlos A
Abstract excerpt
Metabolizing enzymes, which often display genetic polymorphisms, are involved in the activation of compounds present in tobacco smoke that may be relevant to gastric carcinogenesis. We report the results of a study looking at the association between risk of gastric adenocarcinoma and polymorphisms in genes CYP1A1, CYP1A2, EPHX1, and GSTT1. A nested case-control study was carried out within the European...
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