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Article

A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis.

Journal of cell science - 1 Jan 2007

O'Connor Roddy S, Mills Stephen T, Jones Kristen A, Ho Steffan N, Pavlath Grace K

Abstract excerpt

Skeletal muscle regeneration depends on myoblast migration, differentiation and myofiber formation. Isoforms of the nuclear factor of activated T cells (NFAT) family of transcription factors display nonredundant roles in skeletal muscle. NFAT5, a new isoform of NFAT, displays many differences from NFATc1-c4. Here, we examine the role of NFAT5 in myogenesis. NFAT5+/- mice displayed a defect in muscle regeneration...

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Source

Identifiers

PMID: 17164296
DOI: 10.1242/jcs.03307

Genes

NFAT5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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