Article

Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration

2023-06-13

Abstract excerpt

Muscular atrophy is a mortality risk factor that happens with disuse, chronic disease, and aging. Recovery from atrophy requires changes in several cell types including muscle fibers, and satellite and immune cells. Here we show that Zfp697/ZNF697 is a damage-induced regulator of muscle regeneration, during which its expression is transiently elevated. Conversely, sustained Zfp697 expression in mouse muscle leads...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9ab386c7-6910-59ed-88e8-646a63861de0
DOI: 10.1101/2023.06.12.544338

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regenerationDOI 10.1101/2023.06.12.544338Read

Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and remodelingSemantic proximity Read

Factors Regulating or Regulated by Myogenic Regulatory Factors in Skeletal Muscle Stem CellsSemantic proximity Read

Defective plasticity in dermatomyositis patients muscle stem cells is associated with sustained intrinsic inflammatory signaling and disruption of the histone H3.3 chromatin loading pathwaySemantic proximity Read

Interferon-gamma signaling promotes cartilage regeneration after injurySemantic proximity Read

MicroRNA-223-3p promotes skeletal muscle regeneration by regulating inflammation in miceSemantic proximity Read

Setdb1 safeguards genome integrity in muscle stem cells to allow for regenerative myogenesis and inflammationSemantic proximity Read

Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle RegenerationSemantic proximity Read

MicroRNA-29a in Adult Muscle Stem Cells Controls Skeletal Muscle Regeneration During Injury and Exercise Downstream of Fibroblast Growth Factor-2Semantic proximity Read

The lncRNA SNHG26 drives the inflammatory-to-proliferative state transition of keratinocyte progenitor cells during wound healingSemantic proximity Read

Transcriptomic Characterisation of the Molecular Mechanisms Induced by RGMa During Skeletal Muscle Hyperplasia and HypertrophySemantic proximity Read

Muscle-specific microRNAs as biomarkers of Duchenne Muscular Dystrophy progression and response to therapiesSemantic proximity Read

TNF-α Induced Myotube Atrophy in C2C12 Cell Line Uncovers Putative Inflammatory-Related lncRNAs Mediating Muscle WastingSemantic proximity Read