Article
Differentiation of prostate epithelial cell cultures by matrigel/ stromal cell glandular reconstruction.
In vitro cellular & developmental biology. Animal - 1 Jan 2000
Lang Shona H, Smith Joel, Hyde Catherine, Macintosh Catherine, Stower Michael, Maitland Norman J
Abstract excerpt
Three-dimensional epithelial culture models are widely used to emulate a more physiologically relevant microenvironment for the study of genes and signaling pathways. Prostate epithelial cells can grow into solid cell masses or acinus-like spheroids in Matrigel. To test if the ability to form acinus-like spheroids in Matrigel is dependent on how undifferentiated a cell is or whether it is tumor or nontumor, we...
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