Article
Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Dec 2006
Yamazaki H, Okayama A, Imai N, Guengerich F P, Shimizu M
Abstract excerpt
The aim of this study was to investigate the inter-individual variations in cytochrome P4502J2 (CYP2J2) and its typical drug oxidation activities in human liver microsomes in both Japanese and Caucasian populations. CYP2J2 contents were determined immunochemically in liver microsomes from 20 Japa...
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