Article
CYP2J2*7 single nucleotide polymorphism in a Chinese population.
Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2006
Wang Haijian, Jiang Yan, Liu Yang, Lin Chengzhao, Cheng Gang, Chen Xiaoping, Hao Bingtao, Tan Wen, Lin Dongxin, He Fuchu
Abstract excerpt
BACKGROUND: Human cytochrome P450 2J2 (CYP2J2) is the major arachidonic acid epoxygenase that plays important roles in the pathogenesis of a variety of diseases such as cardiovascular disorders and cancers, this P450 also plays a role in the metabolism of some antihistamine drugs. Variability of CYP2J2 gene is highly constrained except for at its proximal promoter a relatively common and functionally relevant...
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