Article
Relationships of Drosophila melanogaster RECQ5/QE to cell-cycle progression and DNA damage.
FEBS letters - 22 Dec 2006
Nakayama Minoru, Maruyama Sayako, Kanda Hiroshi, Ohkita Noriko, Nakano Katsunori, Ito Fumiaki, Kawasaki Katsumi
Abstract excerpt
Members of the RecQ family of DNA helicases are involved in the cellular response to DNA damage and are regulated in the cell-cycle. However, little is known about RecQ5, one of these members. The level of RECQ5/QE, Drosophila melanogaster RecQ5, was increased after the exposure of cultured cells to methyl-methanesulfonate. Transgenic flies that overexpressed RECQ5/QE in their developing eye primordia showed mild...
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