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Article

Manipulating mitotic recombination in the zebrafish embryo through RecQ helicases.

Genetics - 1 Jun 2007

Xie Jing, Bessling Seneca L, Cooper Timothy K, Dietz Harry C, McCallion Andrew S, Fisher Shannon

Abstract excerpt

RecQ DNA helicases resolve Rad-51-mediated recombination and suppress aberrant homologous recombination. RecQ gene loss is associated with cancer susceptibility and increased mitotic recombination. We have developed an in vivo assay based on a zebrafish pigment mutant for suppression of RecQ activity, and demonstrate that zebrafish RecQ genes have conserved function in suppressing mitotic recombination.

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Identifiers

PMID: 17483412
DOI: 10.1534/genetics.107.072983
PMCID: PMC1894594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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