Article
Polymorphisms in Complement Factor H and Hemicentin-1 genes in a Japanese population with dry-type age-related macular degeneration.
American journal of ophthalmology - 1 Dec 2006
Fuse Nobuo, Miyazawa Akiko, Mengkegale Mingge, Yoshida Madoka, Wakusawa Ryosuke, Abe Toshiaki, Tamai Makoto
Abstract excerpt
PURPOSE: To determine whether polymorphisms in the Complement Factor H (CFH) gene and the Hemicentin-1 gene at the ARMD1 locus are associated with dry age-related macular degeneration (AMD) in Japanese patients. DESIGN: Clinically relevant laboratory investigation. METHODS: Eighty unrelated Japanese patients with dry AMD and 196 Japanese control patients were studied. Two exons of the CFH gene and four exons of...
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