Article
Complement factor H polymorphisms in Japanese population with age-related macular degeneration.
Molecular vision - 6 Mar 2006
Okamoto Haru, Umeda Shinsuke, Obazawa Minoru, Minami Masayoshi, Noda Toru, Mizota Atsushi, Honda Miki, Tanaka Minoru, Koyama Risa, Takagi Ikue, Sakamoto Yoshihiro, Saito Yoshihiro, Miyake Yozo, Iwata Takeshi
Abstract excerpt
PURPOSE: To study the frequency of five haplotypes previously reported in the complement factor H (CFH) gene for Japanese patients with age-related macular degeneration (AMD). METHODS: Genomic DNA was isolated from peripheral blood samples taken from 96 Japanese AMD patients and 89 age-matched controls. All patients were diagnosed as having exudative (wet-type) AMD. The amplified polymerase chain reaction (PCR)...
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