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Article

Complement factor H variant increases the risk for early age-related macular degeneration.

Retina (Philadelphia, Pa.) - 1 Jan 2000

Lin Jane-Ming, Tsai Yi-Yu, Wan Lei, Lin Hui-Ju, Tsai Yushin, Lee Cheng-Chun, Tsai Chang-Hai, Tsai Fuu-Jen, Tseng Sung-Huei

Abstract excerpt

PURPOSE: To investigate whether a polymorphism in the complement factor H gene determines the risk for the development of early age-related macular degeneration (AMD). METHODS: In this retrospective case-control study, we enrolled 133 unrelated Taiwan Chinese patients with early AMD and 180 age- and sex-matched control subjects. Early AMD was defined as the presence of extensive intermediate drusen or any large,...

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PMID: 18784628
DOI: 10.1097/IAE.0b013e318184661d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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