Article
No association of complement factor H gene polymorphism and age-related macular degeneration in the Japanese population.
Retina (Philadelphia, Pa.) - 1 Jan 2000
Uka Junko, Tamura Hiroki, Kobayashi Takayuki, Yamane Ken, Kawakami Hideshi, Minamoto Atsushi, Mishima Hiromu K
Abstract excerpt
PURPOSE: The aim of this study was to determine whether genetic polymorphism of complement factor H (CFH) is associated with age-related macular degeneration (AMD) in the Japanese population. METHODS: Genomic DNA was examined in a cohort of 67 Japanese patients with AMD and 107 controls. TT/TC/CC genotypes on exon 9 were screened for sequence alternation by polymerase chain reaction analysis and through...
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